You should now be prepared to tackle the layouts and rendering of all the content that you want to add to your Umbraco website. In particular, you should be well aware of the following concepts:
Working with .NET master pages and child master pages to render the content from your content tree
Being confident that the HTML markup you put in is what comes out when your website is rendered by Umbraco
Using Umbraco specific tags to output content values and manipulating the way the values are rendered
Knowing how to best work with images as assets to your layouts versus images needed for content creation
Incorporating your own styles to impose stylistic rules on content editors via the Rich Text Editor